Database of genome-scale metabolic models

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Revision as of 08:15, 26 September 2014 by Molenaar (talk | contribs) (New page: {{Projectproposal |Contact person=Douwe Molenaar |Contact person2=Esther Kuiper |Master areas=Systems Biology |Fulfilled=No }} Genome scale metabolic network reconstruction and the simulat...)

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About Database of genome-scale metabolic models


Genome scale metabolic network reconstruction and the simulation of these networks are important tools for studying the systems biology of metabolism. The notation of information within these models is far from uniform and names for identical reactions across organisms are often inconsistent. By assembling data from different sources these inconsistencies will accumulate. Therefore we try to unite the reaction and species names as much as possible by mapping to unique identifiers and notations, making it possible to make comparisons between a wide range of models. Our aim is to create a database of curated models that is easily accessible and reliable in providing where data came from. The database will connect models from different sources, giving it a good coverage of metabolic reactions across a wide range of organisms. The student will work with this database by creating an online environment for its exploration and use this environment to do comparative studies of different species and models.